Bring the human context into immune therapy development decisions.
We help biotech and pharma R&D teams
understand how biologics interact with the immune system
in clinically relevant samples and conditions,
supporting candidate selection, mechanism validation and translational decisions.
Promising lab data does not always translate into human biology.
Purified systems, endpoint measurements and simplified models are essential to development. But they may not capture dynamic immune behaviour, biologically relevant matrix effects or response variability.
Vixen adds functional human immune context where it can help to inform the next development decision. We look at the mechanism of action that explain patient-response variability.
Better evidence for critical development decisions.
01
Which candidate should move forward?
Candidate selection
Bring interaction, functional and human-context evidence into candidate comparison before downstream
investment increases.
02
Why does it work, or why does it not?
Mechanism validation
Connect molecular interaction with functional immune behaviour to strengthen mechanism-of-action understanding.
03
What changes in human context?
Translational immune profiling
Investigate immune-response variability in clinically relevant conditions to support translational, biomarker and patient-stratification hypotheses.
From interaction to immune function – in human context.
Define the decision
We begin with the biological or development question your team needs to answer.
Characterise the interaction
Where relevant, we investigate real-time binding behaviour, affinity, and standard kinetics. We can extend this into translational kinetics measured directly haematological samples.
Add immune function and biological context
We combine fit-for-purpose functional assays and immune protein read-outs with clinically relevant matrices and samples. To maximize insights, we strengthen overall immune profiling through guided biomarker strategies.
Interpret what matters
We bring the evidence together around the development question – helping your team decide what to advance, investigate further or adapt.
The science behind
our approach
Read our application notes, publications and perspectives on candidate selection, interaction kinetics, functional immune responses and translational immunology.
Our services & technologies
We select and adapt the approach and technology to the biological question: we are tool-aware, not tool-limited.
Our current capacities include among others protein-protein interaction (e.g. SPR), cell-protein interaction affinity (e.g. ligand tracer), functional cell assays (e.g. fluorescent microscopy, cell cultures) and multiplex secretome profiling (e.g. luminex).
Lab supplies
To support you in your assays and lab activity, we offer a range of hardware, lab supplies and kits.
We also remain the exclusive distributor of the WHITE FOx in Europe and your contact for supply, maintenance and application support.
Have a development question where immune context could change the answer? Tell us what decision your team is approaching, what evidence you already have and where the uncertainty remains.