Bring the human context into immune therapy development decisions.
We help biotech and pharma R&D teams
understand how biologics interact with the immune system
in clinically relevant samples and conditions.
This supports candidate selection, mechanism-of-action interpretation
and translational decision-making.
Promising lab data does not always translate into human biology.
Purified systems, endpoint measurements and simplified models are essential to development. But they may not capture dynamic immune behaviour, biologically relevant matrix effects or response variability.
Vixen adds functional human immune context where it can help to inform the next development decision. We look at the mechanism of action that explain patient-response variability.
Better evidence for critical development decisions.
01
Which candidate should move forward?
Candidate selection
Bring interaction, functional and human-context evidence into candidate comparison before downstream
investment increases.
02
Why does it work, or why does it not?
Mechanism validation
Connect molecular interaction with functional immune behaviour to strengthen mechanism-of-action understanding.
03
What changes in human context?
Translational immune profiling
Investigate immune-response variability in clinically relevant conditions to support translational, biomarker and patient-stratification hypotheses.
From interaction to immune function – in human context.
Define the decision
We begin with the biological or development question your team needs to answer.
Characterise the interaction
Where relevant, we investigate real-time binding behaviour, affinity and interaction kinetics. These measurements can be extended into clinically relevant matrices and haematological samples to understand how biological context affects interaction behaviour.
Add immune function and biological context
We combine fit-for-purpose functional assays and immune protein read-outs with clinically relevant matrices and samples. To maximize insights, we strengthen overall immune profiling through guided biomarker strategies.
Interpret what matters
We bring the evidence together around the development question – helping your team decide what to advance, investigate further or adapt.
From scientific insight to lab execution and enabling technologies
The science behind
our approach
We share the scientific thinking that underpins our approach to complex immune-response questions.
Read our application notes, publications and perspectives on candidate selection, interaction kinetics, functional immune responses and translational immunology.
Our services & technologies
Vixen combines scientific consulting, custom assay development and laboratory execution to generate evidence for candidate selection, mechanism-of-action understanding and better-informed translational decisions.
Depending on the project, we combine approaches including real-time interaction analysis, cell–protein interaction measurements, functional immune-cell assays and multiplex protein profiling in clinically relevant matrices and samples.
We are tool-aware, not tool-limited: we select and adapt the methods that best fit the development question and the evidence required.
Lab supplies
For teams running assays in-house, we provide the tools, consumables and application support needed to build and maintain your workflows.
As the exclusive distributor of the WHITE FOx in Europe, Vixen remains your contact for supply, maintenance and application support.
Have a development question where immune context could change the answer? Tell us what decision your team is approaching, what evidence you already have and where the uncertainty remains.