Functional immunology: our service offering
Vixen Bio helps biotech and pharma R&D teams understand how biologics bind, interact with immune components and behave in relevant sample contexts. Each study is scoped around the development question and evidence your team needs to interpret.
SERVICE AREAS
One development question, three connected layers of biological insight.
Start with the question that matters most, or combine approaches for a more complete biological picture.
01 / ENGAGE
Binding & target engagement
Characterize real-time interaction, affinity and receptor binding in biologically relevant matrices.
02 / FUNCTION
Functional characterization
Explore how molecular interactions activate or modulate immune pathways and drive functional responses, revealing potency and mechanism of action.
03 / TRANSLATE
Translational profiling
Investigate systemic immune responses in human samples to understand donor variability, immune status and potential indicators of immunogenicity.
Methods & technologies
Choose methods that fit the biology.
The analytical toolkit we choose to use depends on the target, sample matrix, required readout and development question.
Surface Plasmon Resonance (SPR)
Real-time interaction analysis and selected quantitation, including fibre-optic Surface Plasmon Resonance (SPR) with WHITE FOx and sensor probes.
Cell-binding & functional assays
Fluorescence-based antibody–cell binding, microscopy and selected functional immune-cell measurements, scoped to the study.
ELISA & multiplex profiling
Targeted immune-protein and multiplex readouts, including Luminex xMAP where suited to the biological question.
Pairing with structural analysis
For selected studies, interaction measurements can be paired with partner-supported mass-spectrometry analysis.
WAYS TO WORK TOGETHER
Scope the work to the study question.
We tailor the scope to each unique project and offer flexible entry and exit points. Start with the decision your team needs to make.
Then we define the assay, sample analysis and level of validation that fit the study objective together.
01 / DEFINE
Study question
Align study design with your candidate’s mechanism of action and the key biological questions to be answered.
02 / DEVELOP
Assay development
Custom & RTU assays, from rapid feasibility studies supporting go/no-go decisions to fully developed methods.
03 / MEASURE
Sample analysis
From focused measurements to integrated studies, we analyze your samples to uncover biological insights and guide next decisions.
04 / QUALIFY
Validation & reporting
Tailor qualification, validation and reporting to your needs, from research-grade to regulatory-aligned requirements.
Scientific resources
Explore the work behind the services.
Short, relevant reading sits beside each service area so you can see how the methods connect to development questions.
From Buffer to Patients
Service and technology overview
Interaction, function and human context.
sdAb kinetics
Streamline mAb characterization
Bioreactor quantitation
Affinity maturation in SLE
Start a conversation
What biology do you need to understand?
Tell us what decision your team is approaching, what evidence you already have and where the uncertainty remains. We can discuss a suitable study scope with you.