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Leading to patient-dependent affinity

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“From buffer to Patients: Affinity assay predicting therapeutic behaviour in patients” Why Measuring Affinity in Native Plasma Matters for Therapeutic Development Affinity defines how strongly a therapeutic antibody binds to its target — and it is one of the most important parameters influencing efficacy, dosing, and clinical performance. Traditionally, affinity is measured in purified systems. […]

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De-risk your sdAbs pipeline with superior selection in physiological conditions

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Kinetic affinity comparison of candidates under actual clinical conditions for more predictive development Singledomain antibodies (sdAbs) have an improved capacity to penetrate tissues and reach obscured targets, making them powerful alternatives to conventional antibodies as therapeutic, whether it’s an inhibiting or neutralising function, or as the high precision binder in CAR-T therapy. Although these may

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